Tom ntej no -Tsim Sterile Processing rau Biopharmaceutical & Food Industries
PebAutomated CIP Fermentation Systemredefines aseptic processing nrog ib tug huv huv kev sib koom ua ke - nyob rau hauv - qhov chaw architecture uas tshem tawm hla - kis kab mob txaus ntshai thaum lub sij hawm ua kom ntau lawm uptime. Tsim los rau GMP-raws li biopharmaceutical manufacturing, precision fermentation, thiab zaub mov-qib microbial cultivation, no turnkey tov combines advanced automation nrog microbial ntim engineering.
Core System Qhov zoo
1. Patented CIP Technology
360℃sprayball npog with validated coverage factor >95%
Ntau -zone tu circuitsrau tank, kav dej, thiab sau manifolds
Automated TACT saib xyuas(Lub Sijhawm, Kev Ua Haujlwm, Kev Cuam Tshuam, Kub)
Tuag- txhais ceg pub dawbnrog<1.5D pipe geometry throughout
2. Zero-Kev Tiv Thaiv Kab Mob
Triple -Seal agitator systemnrog sterile barrier technology
Positive siab cascadeHauv cov cheeb tsam tseem ceeb (ISO Class 5 sib npaug)
Kev ncaj ncees- kuaj cov kab mob me me(0.2μm hydrophobic PTFE)
Bio-decontamination cyclesnrog vaporized hydrogen peroxide xaiv
3. Ntse Automation Nta
Daim ntawv qhia -tsav CIP ib ntus(20+ ua ntej-cov kev pabcuam raug cai)
Tus kheej - kuaj xyuas nozzle clogslos ntawm kev saib xyuas qhov sib txawv
Automated tuav- tswj lub sijhawmnruab nrab ntawm batch
Paperless validationnrog 21 CFR Part 11 ua raws cov ntaub ntawv teev tseg
Technical Specifications
| Parameter | Kev ua tau zoo Standard |
|---|---|
| Volume Range | 50L - 10,000L (kev cai configurations muaj) |
| CIP Efficiency | 6-log txo rauB. subtilisspores |
| Khoom siv | 316L electropolished (Ra Tsawg dua lossis sib npaug ntawm 0.5μm) lossis Hastelloy® |
| Kev ntsuas siab | -1 mus rau 3 bar (muaj peev xwm nqus tau tag nrho) |
| Kub Hloov | Jacketed rau SIP ntawm 121℃/ 250℃F |
| Kev sib txuas | OPC-UA, MODBUS, Profinet |
Qhov System Cheebtsam
1. Core Vessel Nta:
Laser -aligned agitator(magnetic los yog mechanical drive)
Tsis yog -invasive sensors(pH, DO, biomass, conductivity)
Cryogenic txias kev xaivrau cov txheej txheem thermosensitive
2. CIP Infrastructure:
Ntau - tank skid(pre-yuav, caustic, acid, PW, WFI)
Hloov pauv tau - zaus chemical dosing twj
Conductivity- tswj xyuas cov dej huv
3. Automation Suite:
Batch historiannrog kev twv twv twv algorithms
Kev soj ntsuam kev ua haujlwm nyob debntawm IIoT rooj vag
AI- pab tu kom zoo
Validation & Ua raws
Ua ntej -installation:
3D CFD tsom xam ntawm kev khiav dynamics
Cov ntaub ntawv pov thawj (ASME BPE, EDQM)
Ncej - kev teeb tsa:
ATP swab kuaj raws tu qauv
Ntxuav chav nkag mus kawm
Kev ntsuam xyuas duab ntxoov ntxoo rau cov tshuaj tsuag
Kev lag luam kev siv
Biopharma:mAb ntau lawm, tsim tshuaj tiv thaiv
Precision fermentation:Lwm cov proteins, enzymes
Cell Culture:Stem cell kho, kab mob vectors
Khoom noj khoom haus Tech:Probiotics, microbial biomass
Cov txiaj ntsig ua haujlwm
✅ 30% kev hloov pauv sai duavs. phau ntawv tu
✅ Txuag dej mus txog 40%nrog kaw - voj rinsing
✅ Tshem tawm 92% ntawm cov xwm txheej sib kis
✅ Cov lus ceeb toom txog kev saib xyuasrau gaskets / seals
Vim li cas peb CIP Fermentation System?
Ua pov thawj hauv 50+ kev teeb tsahla 3 lub teb chaws
Ib leeg - lub luag haujlwmlos ntawm kev tsim mus rau validation
Yav tom ntej -pab architecturerau kev siv QbD
Lifecycle tus nqi kom zoo duanrog<2% annual downtime
Kev xaiv yuav khoom
Standard Systems:Ua ntej-engineered 50L-2000L configurations
Kev daws teeb meem:Haum rau cov kab mob tshiab lossis cov khoom lag luam
Txhim kho pob:Retrofit uas twb muaj lawm fermenters nrog CIP automation
Txhua qhov system muaj xws li:
FAT / SAT cov ntaub ntawv pob
Kev cob qhia tus neeg ua haujlwm simulator
3-xyoo kev ua haujlwm warranty
